Controlled release of minocycline HCl maintains therapeutic levels of antibiotic up to 21 days
Unique microsphere delivery system
How ARESTIN® Microspheres Work
ARESTIN® is a powder that contains the antibiotic minocycline Hydrochloride, or minocycline HCl, embedded in a polymer base that is easily absorbed by the body. It comes in easy-to-use, unit-dose cartridges that provide effective drug concentrations directly at the site of infection.
ARESTIN® microspheres release minocycline over time, and are completely reabsorbed into the body.
When ARESTIN® is inserted, it immediately adheres to the periodontal pocket. Moisture in the patient's mouth begins to break down (hydrolyze) the polymer, causing water-filled channels to form inside the microspheres. This allows a controlled, sustained release of minocycline.
Treatment with ARESTIN® helps kill the bacteria that underlie periodontal disease, to create a healthier environment.
About Minocycline HCl
ARESTIN® (minocycline HCl) microspheres, 1 mg contains the broad-spectrum antibiotic minocycline, a member of the tetracycline class of antibiotics.
Minocycline Effectively Treats Periodontal Pathogens
Minocycline achieves minimum inhibitory concentration levels well above those required for common periodontal pathogens. This effectively treats the harmful red complex bacteria that cause periodontal disease.
Other Benefits of Tetracycline Derivatives
Minocycline also inhibits enzymes and other molecules that destroy elements of the periodontium, including collagen, elastic fibers, proteoglycans, and fibroconectin.
For full safety information, click here.
See ARESTIN® in Action
ARESTIN® Mechanism of Action Video
