ARESTIN® plus SRP provides nearly twice the reduction in red complex bacteria quantity as SRP alone

50% decrease in RCB quantity achieved with ARESTIN®

ARESTIN® kills the red complex bacteria (RCB) most closely associated with periodontal disease. RCB are:

  • P gingivalis
  • T denticola
  • T forsythia

In a recent study of 127 patients with moderate-to-severe periodontitis and at least 5 teeth with ≥5mm pocket depths, ARESTIN® plus scaling and root planing (SRP) significantly reduced the quantity (P=0.002) and proportions (P=0.0005) of RCB compared with SRP alone.

Reduction in RCB quantity

ARESTIN® + SRP lowered RCB proportions to the level associated with a healthier environment.

Unlike SRP alone, ARESTIN® plus SRP reduced bacteria even 30 days after treatment.

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ARESTIN® is indicated as an adjunct to scaling and root planing (SRP) procedures for reduction of pocket depth in patients with adult periodontitis. ARESTIN® may be used as part of a periodontal maintenance program, which includes good oral hygiene and SRP.

IMPORTANT SAFETY INFORMATION

ARESTIN® should not be used in any patient who has a known sensitivity to minocycline or tetracyclines. The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of the teeth, and therefore should not be used in children or in pregnant or nursing women. Hypersensitivity reactions that included, but were not limited to, anaphylaxis, angioneurotic edema, urticaria, rash, swelling of the face and pruritus have been reported with the use of ARESTIN®. In clinical trials, the most frequently reported nondental treatment-emergent adverse events were headache, infection, flu syndrome and pain.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

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