Safe and well tolerated in clinical trials

Rates of adverse events similar to those seen with placebo

Adverse events reported by treatment group in >3% of the combined clinical trial population of multi-center US trials

ARESTIN® is indicated as an adjunct to scaling and root planing (SRP) procedures for reduction of pocket depth in patients with adult periodontitis. ARESTIN® may be used as part of a periodontal maintenance program, which includes good oral hygiene, and SRP.

ARESTIN® contains minocycline, a tetracycline derivative, and therefore should not be used in children and in pregnant or nursing women. The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of the teeth.

The most common treatment-emergent adverse events were headache (9.0%), infection (7.6%), flu syndrome (5.0%), and pain (4.3%). These occurred at a similar rate to SRP alone and SRP + placebo.

Please see accompanying full Prescribing Information.